GastroSoothe-HP is a blend of botanical extracts and nutrient complexes with specific antimicrobial and mucosal healing properties. These ingredients, mastic (Pistacea lentiscus), methylmethioninesulfonium (“vitamin u”), zinc-carnosine (PepZin-GI) and vitamin C provide activity against Helicobacter pylori, the bacteria associated with ulceration. Mastic, a resinous substance from a tree originally native to the island of Chios in Greece, has a long historic use in the Mediterranean and Middle-east regions of the world where it has been chewed like gum in the treatment of stomach pain for centuries. Methylmethioninesulfonium, a derivative of methionine found in raw cabbage, is often referred to as “vitamin u” because of its history of treating peptic ulcers. The use of raw cabbage juice has been studied extensively, particularly in Russia and other countries of the former Soviet Union, for the healing of damaged and eroded intestinal mucosa. Deglycerized licorice (DGL) is also included as a well established anti-ulceration and mucosal healing botanical. Zinc-carnosine (PepZin-GI) was added to this formulation due to the exciting new literature that has been emerging showing the impressive anti-H. pylori and mucosal protective and anti-ulcerative properties this compound, including the ability to protect the intestinal lining against damage due to indomethacin and other strong anti-inflammatory medications often associated with intestinal mucosal damage.